Bioprocess Basics

The scale–up from bench-top bioreactors to larger, pilot systems can seem daunting. The list of user requirements specifications is much longer, and the manufacturer will provide a peculiar drawing called a P&ID. Reading these is second nature to a Bioprocess Engineer. For someone without such a background, this may be a strange concept. Nevertheless, with a bioreactor in the centre of your process, it is vital to link bioprocess technology and mechanical engineering in a schematic representation. This article shows you how to interpret your P&ID and to understand the functionalities of your bioreactor and its capabilities. 

In order to understand the optimum conditions for in-vitro culture, you need to know which natural environment gives the organism what they need to grow and thrive. In addition, a clear understanding of the different growth phases in a bioprocess is essential for selecting a bioprocess strategy.