In situ bioreactors made easy

Techfors-S

Is the first step always the hardest? Not with the Techfors-S. The Techfors-S contains exactly the same components as our bench bioreactors. This ranges from the pumps via the gassing line to the touch screen controller and the associated software. Both beginners as well as process experts will be able to manage easily.

Techfors-S

Compact in-situ sterilizable bioreactor

Optional

Applications
Volume (TV)
Gassing
  • Air
  • CO2
  • N2
  • O2
Sensors
  • Biomass
  • Exit gas analysis (CO2, O2)
  • pCO2
  • Redox
  • Viable cell density
I am interested in:
  • Cleaning-in-Place (CIP)
  • Sterilisation-in-place with integrated steam generator
  • Bioprocess Software

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Techfors-S
Compact in-situ sterilizable bioreactor

Minimum working volume of 3 litres

The double jacket of the Techfors-S vessels guarantees optimum temperature control even at low starting volumes - essential for modern fed-batch fermentations. Thanks to its compact design and mobile stand, the Techfors-S can be used anywhere.

Easy to start with

Is the first step always the hardest? Not with the Techfors-S. The Techfors-S contains exactly the same components as our bench-top bioreactors. This ranges from the pumps via the gassing line to the touch screen controller and the associated software. Both beginners as well as process experts will be able to manage easily.

eve® Bioprocess Platform Software

eve® is able to do more than just plan, control and analyse your bioprocesses. The eve® software integrates workflows, devices, bioprocess information and big data in a web-based platform, with which you can organise your bioprocesses in a web based system.

Features

Vessel
  • Working volume from 3 to 30 l
  • Double jacket made of 316L stainless steel
  • Individually configurable with a selection of different impellers, spargers and special accessories
  • Up to 14 ports for sensors (anti-foam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
  • 1 port in the bottom of the vessel for harvesting/sampling
  • High-performance pumps
  • Basic setup includes four easy-load precision pumps per culture vessel (option of two more)
  • Gravimetric feeding (with external scale)
  • Profile-based pump-speed control with eve®
  • Gassing
  • Customer-specific gassing with up to 5 gas lines
  • Feed via rotameter or mass-flow regulator
  • Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc.
  • Sensors
  • Customers may choose from digital (Modbus) or analog sensors.
  • Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
  • If required, additional sensors and actuators can be connected.
  • 12" Touchscreen Controller
  • Touchscreen with integrated OPC server
  • Reliable measurement and setting of the bioprocess parameters and communication with eve®
  • Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed
  • eve® Bioprocess Platform Software
  • Planning, controlling and analysing bioprocesses
  • Integrated workflows, devices and bioprocess knowledge
  • Integrates bioreactors and analytical instruments, regardless of the manufacturer
  • Web-based project organisation
  • Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
  • Synchronisation of process-related events such as sampling or inoculation
  • Vessels 15 l / 30 l / 42 l
    Working volume 3–10 l / 5,3 l–20 l / 6–30 l
    Dimensions (W x D x H) 1017 mm x 934 mm x 1841 mm
    Drive Direct drive to 1200 min-1
    Temperature Coolant temperature + 5 °C to 79 °C; to 125 °C for sterilisation
    Gassing per vessel up to 4 MFCs
    Pumps per vessel 4 fixed, optional 2 additional variable
    Ports per vessel

    Top plate:
    19 mm    max. 9x

    Vessel bottom:
    25 mm    max. 5x

    Connectivity OPC XML DA via Ethernet
    Parallel operation via touch screen controller -
    Sterilisation Sterilisation-in-Place

    Manuals

    Operating Manual TechCIP (10.1 MB)

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    Operating Manual Techfors-S (9.6 MB)

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    Techfors-S
    Vessels 15 l / 30 l / 42 l
    Working volume 3–10 l / 5,3 l–20 l / 6–30 l
    Dimensions (W x D x H) 1017 mm x 934 mm x 1841 mm
    Drive Direct drive to 1200 min-1
    Temperature Coolant temperature + 5 °C to 79 °C; to 125 °C for sterilisation
    Gassing per vessel up to 4 MFCs
    Pumps per vessel 4 fixed, optional 2 additional variable
    Ports per vessel

    Top plate:
    19 mm    max. 9x

    Vessel bottom:
    25 mm    max. 5x

    Connectivity OPC XML DA via Ethernet
    Parallel operation via touch screen controller -
    Sterilisation Sterilisation-in-Place

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    10 Things to Consider When Buying an In-Situ Sterilizable Bioreactor

    The Techfors-S bioreactor systems have been a key component to our mammalian cells grown in continous culture.
    Eva Bric-Furlong - Automation Specialist and Scientific Research Investigator, Sanofi US

    «Based on a clever and innovative framework, we build the Techfors-S to meet your requirements by using specific adaptations.»

    Raphaël Boillat — Head of Global Distribution Management

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