Minifors 2

Features

Culture vessels	Available in total volumes of 1.5 L, 3 L and 6 L Quick and easy change between culture vessel sizes Rounded flat vessel bottom: Low minimum working volume, good mixing, stability with or without a vessel holder Safe sampling without any dead volume: INFORS HT Super Safe Sampler
Top plate	Intelligent design for easy access to all ports Sufficient ports, for standard fittings and extra inlets, immersion tubes and sensors 4 x 7.5 mm: addition ports available for acid, base, feed & 1 free 4 x 10 mm: sparger, anti-foam system, temperature sensor, sampling/harvest Maximum 7 x 12 mm (Pg13.5): pH, pO₂, exhaust gas cooler, inoculation are pre-allocated, 3 are freely available Convenient, tool-free cleaning and maintenance thanks to knurled screws
High-performance pumps	4 High-performance pumps Configurable operating mode: digital (fixed-speed) or analogue (variable speed) 3 x fix (acid, base, antifoam), 1 x variable (feed) Autoclavable pump heads Gravimetric feeding with dosing mode (requires external scale) Profile-based pump-speed control (with eve^®) 2 analogue inputs / outputs to connect external pumps (version for cell cultures)
Gassing	2 integrated MFC for air, air/O₂, or air/N₂ (version for microorganisms) 5 integrated MFC for air, O₂, N₂, CO₂ and head space gassing (version for cell cultures) Integrated pressure sensor for detecting a blocked filter Gassing optimised for bacteria applications and cell cultures: specific gassing rate (vvm) up to 2.0 min^-1 Multiple cascades for pO₂ control by means of stirrer speed, gassing rate (“TotalFlow”) and/or gas composition (“GasMix”)
Sensors	Robust, digital connection of pH and pO₂ sensors Optical pO₂ sensor: immediately ready for use, no polarization required Calibration data stored in sensor head Product calibration of the pH sensor for reliable measurements during long-running bioprocesses Optional: biomass sensors from Optek and aquila biolabs
Operating unit	Integrated 7" touch screen (17.8 cm) Simple handling through intuitive menus and practical on-screen help Calibration of pH, pO₂ and OD sensors using simple install wizards Direct data export to USB drive in stand-alone operation Multiple display languages
eve^® Bioprocess Platform Software	Planning, controlling and analysing bioprocesses Integrated workflows, devices and bioprocess knowledge Integrates bioreactors and analytical instruments, regardless of the manufacturer Web-based project organisation Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors) Synchronisation of process-related events such as sampling or inoculation

Technical Details

Vessels	1.5 L / 3 L / 6 L
Working volume	0.3–1.0 L / 0.6–2.0 L / 1.1–4.0 L
Dimensions (W x D x H)	455 mm x 375 mm x 740 mm
Drive	Version for Microorganisms: 150 min^-1 to 1600 min^-1 Version for cell cultures: 24 min–1 to 600 min^-1
Temperature	+ 15 °C (Coolant temperature + 5 °C) to 60 °C
Gassing per vessel	Version for microorganisms: 2 MFCs up to 2 min^-1, version for cell cultures: 5 MFCs up to 0.15 min^-1
Pumps per vessel	4 x configurable (fixed or variable speed) ex-works: 3 x fixed (acid, base, anti-foam), 1 x variable (feed)
Pump performance	0.0034 to 3,52 mL min^-1 (standard), 0.017 to 16,13 mL min^-1, 0.0012 to 1.12 mL min^-1
Ports per vessel	7,5 mm 4x 10 mm 4x 12 mm (Pg13,5) max. 7x
Connectivity	OPC UA via Ethernet
Parallel operation via touch screen controller	1 unit
Sterilisation	Autoclave

Downloads

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Application Notes

Biological and process-engineering characterization of the Minifors 2 laboratory bioreactor (429.9 kB)

Process transfer of CHO cultivations using the Minifors 2 as an example (754.3 kB)

Manuals

Brief Instructions Super Safe Sampler (681.5 kB)

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Operating manual Minifors 2 (5.9 MB)

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White Papers

Continuous Culture as the Universal Bioprocess for Manufacturing (934.8 kB)

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Compare

	Minifors 2
Vessels	1.5 L / 3 L / 6 L	0,4 L / 0,75 L / 1,4 L	2 L / 3,6 L / 7,5 L / 13 L	15 l / 30 l / 42 l	up to 1000 L
Working volume	0.3–1.0 L / 0.6–2.0 L / 1.1–4.0 L	0,15–0,25 L / 0,18–0,5 L / 0,32–1 L	0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,2–10 L	3–10 l / 5,3 l–20 l / 6–30 l	up to 660 L
Dimensions (W x D x H)	455 mm x 375 mm x 740 mm	350 mm x 520 mm x 960 mm	464 mm x 462 mm x 996 mm	1017 mm x 934 mm x 1841 mm	Depending on specification
Drive	Version for Microorganisms: 150 min^-1 to 1600 min^-1 Version for cell cultures: 24 min–1 to 600 min^-1	Magnetic drive to 1600 min^-1	Direct drive up to 1500 min^–1	Direct drive to 1200 min^-1	Depending on specification
Temperature	+ 15 °C (Coolant temperature + 5 °C) to 60 °C	Coolant temperature + 5 °C to 70 °C	Coolant temperature + 5 °C bis 70 °C	Coolant temperature + 5 °C to 79 °C; to 125 °C for sterilisation	up to 79 °C for temperature control; up to 125 °C for sterilisation
Gassing per vessel	Version for microorganisms: 2 MFCs up to 2 min^-1, version for cell cultures: 5 MFCs up to 0.15 min^-1	Up to 4 rotameters oder MFCs up to 2 min^-1 (vvm)	Up to 5 rotameters or MFCs up to 2 min^-1 (vvm)	up to 4 MFCs	Depending on specification
Pumps per vessel	4 x configurable (fixed or variable speed) ex-works: 3 x fixed (acid, base, anti-foam), 1 x variable (feed)	3 fixed, 1 variable, optional 1 additional variable	3 fixed, 1 variable, optional 1 additional variable 3	4 fixed, optional 2 additional variable	3 fixed, 1 variable, optional 2 additional
Pump performance	0.0034 to 3,52 mL min^-1 (standard), 0.017 to 16,13 mL min^-1, 0.0012 to 1.12 mL min^-1	Depending on the design from 0,0012 mL min^-1 to 3,46 mL min^-1	Depending on version, from 1,2 μl min^–1 to 17,1 ml min^–1
Ports per vessel	7,5 mm 4x 10 mm 4x 12 mm (Pg13,5) max. 7x	7 mm 4x 10 mm 4x 12 mm (Pg13,5) max. 5x	7 mm max. 4x 10 mm 2x 12 mm (Pg13,5) max. 6x 19 mm max. 6x	Top plate: 19 mm max. 9x Vessel bottom: 25 mm max. 5x	Depending on specification
Connectivity	OPC UA via Ethernet	OPC XML DA via Ethernet	OPC XML DA via Ethernet	OPC XML DA via Ethernet	OPC XML DA via Ethernet
Parallel operation via touch screen controller	1 unit	3 base units, resp. 6 vessels	up to 6 vessels	-	1 base unit
Sterilisation	Autoclave	Autoclave	Autoclave or LabCIP (microbial version)	Sterilisation-in-Place	Sterilisation-in-Place
		Go to Multifors 2	Go to Labfors 5	Go to Techfors-S	Go to Techfors	Go to CGQ BioR	Go to Optek Turbidity Sensors	Go to Super Safe Sampler

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Minifors 2

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