INFORS HT blog

Discover how this company has has significantly improved their bioprocess research and development capabilities with INFORS HT’s Minifors, Labfors, and Techfors bioreactor systems. Explore how these solutions have streamlined operations, optimized yields, and simplified processes, enabling them to provide solutions tailored to specific needs and expanding the practical application of their work.

This article will look at the history and development of a de-facto standard in academic and industrial research laboratories throughput the world, the Multitron incubator shaker. The aim is to show that an initial revolution can lead to evolution, as needs change over time. The fundamentals of a good design can last decades, when new benefits and the best of current technologies are added regularly.

A plasmid DNA production process was performed comparing conventional Erlenmeyer flasks with LB medium and the Thomson’s Ultra Yield® system. E. coli cells were cultivated in both systems in the INFORS HT Multitron incubator shaker, bacterial growth was monitored, and the plasmids were purified at the end of cultivation. Subsequently, the quality of the isolated plasmids was analyzed by HPLC. The combination of the Ultra Yield® flasks with the enriched Plasmid+® medium and the AirOtop® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.

“We want it so every child in the world can pick up a crayon and color the sky and have that crayon that they pick is blue, right, and today that’s not the reality for every kid around the world,” Zara Summers, Chief Science Officer at LanzaTech, a Biotech Company, vividly articulates the company’s goal to reduce fossil fuel consumption and instead, recycle carbon, that is already above ground to create necessities.

In the ever-evolving landscape of biopharmaceutical processes development, companies are constantly seeking ways to enhance efficiency and streamline their operations. One formidable combination that has been gaining momentum is the use of a powerful and easy to use batch planning strategy with eve bioprocessing software and parallel bioreactors Multifors. In this article, we will delve into how the combination of these two tools can enable you to potentiate process development.

The Multitron incubator shaker remains uniquely popular since its launch in 1991. The original concept was to offer maximum shake flask capacity whilst occupying minimum space within the laboratory. A number of other new features were launched alongside the Multitron, and since have become firm favourites with users. Some of the best loved capabilities of the Multitron are listed below.