The solution for biomass measurement in shake flasks

CGQ - Cell Growth Quantifier

The Cell Growth Quantifier (CGQ) is a laboratory device for online monitoring of biomass in shake flasks without taking the flasks out of the incubation shaker. The CGQ determines the biomass concentration automatically and non-invasively by a patented optical measurement. Thus, profound microbial growth kinetics of highest precision can be generated.

CGQ - Cell Growth Quantifier

Online monitoring of biomass in shake flasks

Parallel applications

Suitable for algae, Archaea, bacteria, fungi, plant cells, yeast

Fits ideally on all glass and single-use flasks

Optional

Base station

Flask size

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CGQ - Cell Growth Quantifier
Online monitoring of biomass in shake flasks

Make sense of your bioprocess

Creating a seamless record of biomass concentration allows you to detect bioprocess changes in real time. This lets you identify limitations, inhibiting factors, and contamination a t an early stage. Reproducibility is increased due to a lower error rate when compared with manual biomass measurement.

Parallel applications

Monitor up to 64 shake flasks in parallel one one PC

Real-time measurement

Detailed process monitoring at any given time for a high data density

Can be used for a diverse range of scientific applications

Growth-curve-guided induction of protein expression, media development / optimisation, screening / strain comparisons, detection of limitations and contaminations, analysis of growth kinetics, optimisation of culture conditions, online monitoring of thermophile and phototrophic organisms

Features

Sensor plate	The sensor plate is positioned under the shake flask and measures the biomass non-invasively. It is available for 5 flask sizes.
Cover	Each shake flask can be darkened with a cover to ensure measurements of highest precision and sensitivity.
Base station	The base station designed for 8 or 16 shake flasks bundles the data from all monitored flasks and sends it to the cgQuant software.
CGQuant Software	The cgQuant Software analyses and visualises the biomass signal from all monitored shake flasks.
Compatibility	With the INFORS HT shakers and standard laboratory equipment of all manufacturers. Fits ideally on all glass and single-use flasks (with and without baffles), spring clamps and sticky plates («Sticky Stuff»).

Technical Details

Rotation speed	150 - 350 min^-1 (clamps) 0 - 200 min^-1 (StickyStuff)
Shake flask sizes	100 mL 250 mL 500 mL 1000 mL 2000 mL 5000 mL
Temperature	10 - 50 °C
Ambient humidity (rH)	0 - 80% (non-condensing)
Measuring range	OD₆₀₀ 0,2 to 50¹³
System requirements	Windows 7 or newer with .NET 4.7; Dual Core @ 2 GHz/core; >8 GB RAM; >10 GB HDD

Downloads

Flyer & Brochures

Flyer CGQ (277.3 kB)

Manuals

Operating manual CGQ (3.8 MB)

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White Papers

Integrated Biomass Measurement in Shake Flasks (860.1 kB)

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	CGQ - Cell Growth Quantifier
Rotation speed	150 - 350 min^-1 (clamps) 0 - 200 min^-1 (StickyStuff)		Universal tray: 250 min^-1 (25 mm shaking throw) Sticky Stuff tray: 200 min^-1 (25 mm shaking throw) Sticky Stuff tray: 150 min^-1 (50 mm shaking throw)					200 min^-1 - 300 min^-1 depending on shaking throw and shake flask size
Shake flask sizes	100 mL 250 mL 500 mL 1000 mL 2000 mL 5000 mL							100 ml 250 ml 300 ml 500 ml 1000 ml 2000 ml
Temperature	10 - 50 °C							10 – 45 °C
Ambient humidity (rH)	0 - 80% (non-condensing)							Relative humidity: 0 – 80% (not-condensing)
Measuring range	OD₆₀₀ 0,2 to 50¹³
System requirements	Windows 7 or newer with .NET 4.7; Dual Core @ 2 GHz/core; >8 GB RAM; >10 GB HDD							CPU: min. dual core 2 CHz RAM / HDD: ≥4 GB / ≥10 GB Operating system: Microsoft Windows 7 or newer with JRE 8 and .NET 4.5 Screen resolution: 1920 x 1080 pixels Recommended Web browser: Firefox, Chrome
		Go to Test tube holder for shakers	Go to Box for Microtiter Plates	Go to Universal trays	Go to Fixed-configuration trays	Go to Trays for microtiter plates and deep-well plates	Go to Sticky Stuff	Go to LIS - Liquid Injection System	Go to Celltron	Go to Orbitron	Go to Multitron	Go to Minitron	Go to Ecotron	Go to Multitron Standard	Go to Ecotron	Go to Minitron	Go to Multitron Standard

Integrated Biomass Measurement in Shake Flasks

White Paper on acomprehensive and user-friendly integrated system for biomass cultivation and monitoring

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eve – The Bioprocess Platform Software

One single solution to unify all your equipment and data

The CGQ has enabled us to obtain accurate information on the growth kinetics of hyperthermophilic archaea and has solved the problem of manually generating data for prolonged periods of time and of dealing with evaporation effects due to the high temperature.

Prof. Dr. ir. Eveline Peeters - Group Leader at Vrije Universiteit Brussel, Belgium

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The solution for biomass measurement in shake flasks

CGQ - Cell Growth Quantifier

CGQ - Cell Growth Quantifier

Make sense of your bioprocess

Parallel applications

Real-time measurement

Can be used for a diverse range of scientific applications

Features

Flyer & Brochures

Manuals

White Papers

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5 Ways to Increase Biomass in Your Shake Flasks

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