A truly universal bioreactor

Labfors 5

The Labfors 5 is suitable for cell cultures, microorganisms, phototrophic organisms as well as solid subtrates and enzymatic bioprocesses. There are almost no limits to its uses.

Labfors 5

High-end All-rounder
Up to six fully equipped bioreactors
4 high-performance pumps
Optimum gassing with up to 5 gas lines
eve® Bioprocess Platform Software

Optional

Application
Volume (TV)
Gassing
  • Air
  • CO2
  • N2
  • O2
Sensors
  • Biomass
  • Exit gas analysis (CO2, O2)
  • pCO2
  • Redox
  • Viable cell density
I am interested in:
  • Bioprocess Software
  • CIP/SIP
  • Qualification

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Labfors 5
High-end All-rounder

Fully equipped

An integrated analog feed pump is a standard feature that makes the bioreactor immediately ready for fed-batch cultures. The unit includes three digital pumps for acids, bases and antifoaming agents. Up to four gases (air, N2 , O2 and CO2 ) can be used in virtually any combination. Users can select either a mass-flow regulator or a rotameter for a precise feed. If required, additional sensors and actuators can be connected.

Make six out of one

Would you like to organise your laboratory work more efficiently? Then connect your touchscreen control to up to six Labfors 5 devices. You can operate them simultaneously, and save time by, for example, calibrating all pH or pO2 sensors at the push of a button.

eve® Bioprocess Platform Software

eve® is able to do more than just plan, control and analyse your bioprocesses. The eve® software integrates workflows, devices, bioprocess information and big data in a web-based platform, with which you can organise your bioprocesses in a web based system.

Features

Culture vessels
  • Working volumes ranging between 0.5 and 10 L
  • Can be configured according to individual needs thanks to a selection of different stirrers, spargers and specialized accessories
  • Up to 14 ports for sensors (antifoam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
  • No welded lid components—ideal for GMP applications
  • High-performance pumps
  • Basic setup includes four precision pumps per culture vessel (option of one more)
  • Autoclavable pump heads
  • Gravimetric feeding (with external scale)
  • Profile-based pump-speed control with eve®
  • Gassing
  • Customer-specific gassing with up to 5 gas lines, either via a sparger or in the headspace
  • Feed via rotameter or mass-flow regulator
  • Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc.
  • pH control with acid and CO2
  • Sensors
  • Customers may choose from digital (Modbus) or analog sensors.
  • Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
  • If required, additional sensors and actuators can be connected.
  • Operating unit
  • Touchscreen with integrated OPC server
  • Reliable measurement and setting of the bioprocess parameters and communication with eve®
  • Parallel management and control of up to six devices
  • Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed
  • eve® Bioprocess Platform Software
  • Planning, controlling and analysing bioprocesses
  • Integrated workflows, devices and bioprocess knowledge
  • Integrates bioreactors and analytical instruments, regardless of the manufacturer
  • Web-based project organisation
  • Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
  • Synchronisation of process-related events such as sampling or inoculation
  • Vessels 2 L / 3,6 L / 7,5 L / 10 L (cell version) / 13 L
    Working volume 0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,1–7 L (cell version) / 2,2–10 L
    Dimensions (W x D x H) 464 mm x 462 mm x 996 mm
    Drive Magnetic drive up to 300 min–1 (cell version); direct drive up to 1500 min–1
    Temperature Coolant temperature + 5 °C bis 70 °C bzw. 95 °C
    Gassing per vessel up to 5 rotameters or MFCs up to 2 min-1 (vvm) or 0.1 min-1 (cell version)
    Pumps per vessel 3 fixed, 1 variable, optional 1 additional variable 3
    Pump performance Depending on version, from 1,2 μl min–1 to 17,1 ml min–1
    Ports per vessel

      7 mm                max. 4x 
    10 mm                2x
    12 mm (Pg13,5) max. 6x
    19 mm                max. 6x

    Connectivity OPC XML DA via Ethernet
    Parallel operation via touch screen controller up to 6 vessels
    Sterilisation Autoclave or LabCIP (microbial version)

    Application Notes

    Manuals

    Brief Instructions Super Safe Sampler (681.5 kB)

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    Operating manual Gas Analyser (1.4 MB)

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    Operating manual LabCIP (5.6 MB)

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    Operating manual Labfors 5 version for cell cultures (8.2 MB)

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    Operating manual Labfors 5 version for cell cultures - Single use (427.7 kB)

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    Operating manual Labfors 5 version for microorganisms (8.1 MB)

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    Operating manual Labfors 5 version for phototrophic organisms (7.9 MB)

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    Operating manual Labfors 5 version for solid-state and enzymatic bioprocesses (7.2 MB)

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    Operating manual Touchscreen Software V 3.0 (3.6 MB)

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    White Papers

    Continuous Culture as the Universal Bioprocess for Manufacturing (934.8 kB)

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    Labfors 5
    Vessels 2 L / 3,6 L / 7,5 L / 10 L (cell version) / 13 L
    Working volume 0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,1–7 L (cell version) / 2,2–10 L
    Dimensions (W x D x H) 464 mm x 462 mm x 996 mm
    Drive Magnetic drive up to 300 min–1 (cell version); direct drive up to 1500 min–1
    Temperature Coolant temperature + 5 °C bis 70 °C bzw. 95 °C
    Gassing per vessel up to 5 rotameters or MFCs up to 2 min-1 (vvm) or 0.1 min-1 (cell version)
    Pumps per vessel 3 fixed, 1 variable, optional 1 additional variable 3
    Pump performance Depending on version, from 1,2 μl min–1 to 17,1 ml min–1
    Ports per vessel

      7 mm                max. 4x 
    10 mm                2x
    12 mm (Pg13,5) max. 6x
    19 mm                max. 6x

    Connectivity OPC XML DA via Ethernet
    Parallel operation via touch screen controller up to 6 vessels
    Sterilisation Autoclave or LabCIP (microbial version)
    We are thoroughly impressed by the practical design. It allows us to save time during calibration and preparation for cultivation.
    Mohd RazifMamat - Head Of Technical Administration & Operation, Malaysia Genome Institute

    «Our most versatile and freely configurable benchtop bioreactor, which can handle even the most complex PAT applications.»

    Eric Abellan — Product Manager Software

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