Labfors 5

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Fully equipped

An integrated analog feed pump is a standard feature that makes the bioreactor immediately ready for fed-batch cultures. The unit includes three digital pumps for acids, bases and antifoaming agents. Up to four gases (air, N₂ , O₂ and CO₂ ) can be used in virtually any combination. Users can select either a mass-flow regulator or a rotameter for a precise feed. If required, additional sensors and actuators can be connected.

Make six out of one

Would you like to organise your laboratory work more efficiently? Then connect your touchscreen control to up to six Labfors 5 bioreactors. You can operate them simultaneously, and save time by, for example, calibrating all pH or pO₂ sensors at the push of a button.

eve^® Bioprocess Platform Software

eve^® is able to do more than just plan, control and analyse your bioprocesses. The eve^® software integrates workflows, devices, bioprocess information and big data in a web-based platform, with which you can organise your bioprocesses in a web based system.

Features

Culture vessels	Working volumes ranging between 0.5 and 10 L Can be configured according to individual needs thanks to a selection of different stirrers, spargers and specialized accessories Up to 14 ports for sensors (antifoam, optical density, pH, pO₂, redox, conductivity, live cell density, etc.) No welded lid components—ideal for GMP applications
High-performance pumps	Basic setup includes four precision pumps per culture vessel (option of one more) Autoclavable pump heads Gravimetric feeding (with external scale) Profile-based pump-speed control with eve^®
Gassing	Customer-specific gassing with up to 5 gas lines Feed via rotameter or mass-flow regulator Cascades may be configured in serial or in parallel for controlling the pO₂ via the stirrer speed, gassing rate, gas composition, etc.
Sensors	Customers may choose from digital (Modbus) or analog sensors. Product calibration of the pH sensor for reliable measurements during long-running bioprocesses If required, additional sensors and actuators can be connected.
12" Touchscreen Controller	Touchscreen with integrated OPC server Reliable measurement and setting of the bioprocess parameters and communication with eve^® Parallel management and control of up to six devices Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO₂, anti-foaming agent, feed
eve^® Bioprocess Platform Software	Planning, controlling and analysing bioprocesses Integrated workflows, devices and bioprocess knowledge Integrates bioreactors and analytical instruments, regardless of the manufacturer Web-based project organisation Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors) Synchronisation of process-related events such as sampling or inoculation

Technical Details

Vessels	2 L / 3,6 L / 7,5 L / 13 L
Working volume	0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,2–10 L
Dimensions (W x D x H)	464 mm x 462 mm x 996 mm
Drive	Direct drive up to 1500 min^–1
Temperature	Coolant temperature + 5 °C bis 70 °C bzw. 95 °C
Gassing per vessel	Up to 5 rotameters or MFCs up to 2 min^-1 (vvm)
Pumps per vessel	3 fixed, 1 variable, optional 1 additional variable 3
Pump performance	Depending on version, from 1,2 μl min^–1 to 17,1 ml min^–1
Ports per vessel	7 mm max. 4x 10 mm 2x 12 mm (Pg13,5) max. 6x 19 mm max. 6x
Connectivity	OPC XML DA via Ethernet
Parallel operation via touch screen controller	up to 6 vessels
Sterilisation	Autoclave or LabCIP (microbial version)

Compare

	Labfors 5
Vessels	2 L / 3,6 L / 7,5 L / 13 L	1.5 L / 3 L / 6 L	0,4 L / 0,75 L / 1,4 L	15 l / 30 l / 42 l	up to 1000 L
Working volume	0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,2–10 L	0.3–1.0 L / 0.6–2.0 L / 1.1–4.0 L	0,15–0,25 L / 0,18–0,5 L / 0,32–1 L	3–10 l / 5,3 l–20 l / 6–30 l	up to 660 L
Dimensions (W x D x H)	464 mm x 462 mm x 996 mm	455 mm x 375 mm x 740 mm	350 mm x 520 mm x 960 mm	1017 mm x 934 mm x 1841 mm	Depending on specification
Drive	Direct drive up to 1500 min^–1	Version for Microorganisms: 150 min^-1 to 1600 min^-1 Version for cell cultures: 24 min–1 to 600 min^-1	Magnetic drive to 1600 min^-1	Direct drive to 1200 min^-1	Depending on specification
Temperature	Coolant temperature + 5 °C bis 70 °C bzw. 95 °C	Coolant temperature + 10 °C to 60 °C	Coolant temperature + 5 °C to 70 °C	Coolant temperature + 5 °C to 79 °C; to 125 °C for sterilisation	up to 79 °C for temperature control; up to 125 °C for sterilisation
Gassing per vessel	Up to 5 rotameters or MFCs up to 2 min^-1 (vvm)	Version for microorganisms: 2 MFCs up to 2 min^-1, version for cell cultures: 5 MFCs up to 0.15 min^-1	Up to 4 rotameters oder MFCs up to 2 min^-1 (vvm)	up to 4 MFCs	Depending on specification
Pumps per vessel	3 fixed, 1 variable, optional 1 additional variable 3	4 x configurable (fixed or variable speed) ex-works: 3 x fixed (acid, base, anti-foam), 1 x variable (feed)	3 fixed, 1 variable, optional 1 additional variable	4 fixed, optional 2 additional variable	3 fixed, 1 variable, optional 2 additional
Pump performance	Depending on version, from 1,2 μl min^–1 to 17,1 ml min^–1	0.0034 to 3,52 mL min^-1 (standard), 0.017 to 16,13 mL min^-1, 0.0012 to 1.12 mL min^-1	Depending on the design from 0,0012 mL min^-1 to 3,46 mL min^-1
Ports per vessel	7 mm max. 4x 10 mm 2x 12 mm (Pg13,5) max. 6x 19 mm max. 6x	7,5 mm 4x 10 mm 4x 12 mm (Pg13,5) max. 7x	7 mm 4x 10 mm 4x 12 mm (Pg13,5) max. 5x	Top plate: 19 mm max. 9x Vessel bottom: 25 mm max. 5x	Depending on specification
Connectivity	OPC XML DA via Ethernet	OPC UA via Ethernet	OPC XML DA via Ethernet	OPC XML DA via Ethernet	OPC XML DA via Ethernet
Parallel operation via touch screen controller	up to 6 vessels	1 unit	3 base units, resp. 6 vessels	-	1 base unit
Sterilisation	Autoclave or LabCIP (microbial version)	Autoclave	Autoclave	Sterilisation-in-Place	Sterilisation-in-Place
		Go to Minifors 2	Go to Multifors 2	Go to Techfors-S	Go to Techfors	Go to CGQ BioR	Go to Optek Turbidity Sensors	Go to Super Safe Sampler

Batch cultivation of microalgae in Labfors 5

Application Note on how the luminostat control allows for a fast increase in biomass while limiting overexposure to light and the waste of light energy.

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