INFORS HT blog

A plasmid DNA production process was performed comparing conventional Erlenmeyer flasks with LB medium and the Thomson’s Ultra Yield® system. E. coli cells were cultivated in both systems in the INFORS HT Multitron incubator shaker, bacterial growth was monitored, and the plasmids were purified at the end of cultivation. Subsequently, the quality of the isolated plasmids was analyzed by HPLC. The combination of the Ultra Yield® flasks with the enriched Plasmid+® medium and the AirOtop® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.

“We want it so every child in the world can pick up a crayon and color the sky and have that crayon that they pick is blue, right, and today that’s not the reality for every kid around the world,” Zara Summers, Chief Science Officer at LanzaTech, a Biotech Company, vividly articulates the company’s goal to reduce fossil fuel consumption and instead, recycle carbon, that is already above ground to create necessities.

In the ever-evolving landscape of biopharmaceutical processes development, companies are constantly seeking ways to enhance efficiency and streamline their operations. One formidable combination that has been gaining momentum is the use of a powerful and easy to use batch planning strategy with eve bioprocessing software and parallel bioreactors Multifors. In this article, we will delve into how the combination of these two tools can enable you to potentiate process development.

The Multitron incubator shaker remains uniquely popular since its launch in 1991. The original concept was to offer maximum shake flask capacity whilst occupying minimum space within the laboratory. A number of other new features were launched alongside the Multitron, and since have become firm favourites with users. Some of the best loved capabilities of the Multitron are listed below.

At INFORS HT, our mission is to provide superior products and services that improve bioprocess workflows and enable our customers to focus on their core mission. We believe in the power of partnerships that drive innovation, foster growth and deliver exceptional results. Hence we are thrilled to share the success story of FairJourney Biologics, an innovative Contract Research Organization specialized in Antibody Discovery and Production.

Your lab depends on healthy growing cells, and these cells depend on the continuous operation of your incubation shakers. The last thing you want in your lab is unscheduled downtime.  

Servicing your incubation shaker is important to maintain accuracy, prevent contamination, optimize productivity and extend lifespan, especially if you use it in a laboratory for research or production settings where precision, reliability and consistency are crucial.