Invasive turbiditiy sensors for online biomass measurement

Optek

The Optek-ASD sensors are mounted in a port (12 mm or 25 mm) on the top plate of the vessel. Using the NIR absorption the sensors provide data on the growth of microorganisms and cell cultures

Optek

Invasive online biomass measurement
Control based on results and real-time analysis
Makes bioprocess optimization faster and easier

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Optek
Invasive online biomass measurement

Control based on results and real-time analysis

The eve® bioprocess platform software can seamlessly monitor growth kinetics in real time, document them, and compare them to those of earlier batches. These biomass data can be used for process control tasks in jobs such as generating feeding profiles or using growth curves as a basis for inducing protein product.

Ideal for a wide range of scientific applications

Directly comparing growth curves allows scientists to screen a variety of media and bacterial strains in detail, thereby optimizing bioprocess conditions and cell clones in very little time.

Make sense of your bioprocess

Creating a seamless record of biomass concentration allows you to detect bioprocess changes in real time.  This lets you identify limitations, inhibiting factors, and contamination a t an early stage. Reproducibility is increased due to a lower error rate when compared with manual biomass measurement.

Features

Combatibility
  • Ideal for scale-up processes
  • Path length suitable for high-density microbial applications and low-density cell cultures alike
  • Bioprocess Platform software eve®
  • Control based on results (i.e., induction of a specific cell density, etc.)
  • Easy to create complex feeding profiles based on biomass developmentt
  • Compare growth curves from different batches quickly
  • Comprehensive documentation of data gathered
  • Clear, comprehensive documentation for the data acquired
  •  Soft sensor for correlating measured values with parameters such as OD or dry biomass
  • Premium quality
  • Compact, robust design with a measurement segment optimized for flow and sterilization technologies
  • All components in contact with media are made of electropolished stainless steel
  • Measuring modes OPL01: for very high cell densities; OPL05: for higher cell densities; OPL10: for lower cell densities
    Measuring wavelength 840 nm – 910 nm
    OD range Different sensors (OPL) for changing OD ranges
    Measuring principle Single-channel light absorption
    Detector silicon photo diode (hermetically-sealed)
    Light source Hybrid LED
    Temperature up to 50 °C
    Cleansing Autoclaving after every use
    No documents
    Optek
    Measuring modes OPL01: for very high cell densities; OPL05: for higher cell densities; OPL10: for lower cell densities
    Measuring wavelength 840 nm – 910 nm
    OD range Different sensors (OPL) for changing OD ranges
    Measuring principle Single-channel light absorption
    Detector silicon photo diode (hermetically-sealed)
    Light source Hybrid LED
    Temperature up to 50 °C
    Cleansing Autoclaving after every use

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    Simon Egli — Director Sales

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