INFORS HT blog

The scale–up from bench-top bioreactors to larger, pilot systems can seem daunting. The list of user requirements specifications is much longer, and the manufacturer will provide a peculiar drawing called a P&ID. Reading these is second nature to a Bioprocess Engineer. For someone without such a background, this may be a strange concept. Nevertheless, with a bioreactor in the centre of your process, it is vital to link bioprocess technology and mechanical engineering in a schematic representation. This article shows you how to interpret your P&ID and to understand the functionalities of your bioreactor and its capabilities. 

Freeing a port on a small bioreactor can increase its capability. We give you some practical examples how to allow a small bioreactor to outperform its original design limitations.

Using laboratory shakers in CO2 incubators has become a standard in many labs. However, for a successful outcome there are a couple of key factors that everyone should be aware of.

Several key factors are essential for successful fermentation of pichia pastoris. Here comes a brief and simple overview on what is needed for process optimization in terms of the capability of the hardware used.  

Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from Covid-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.