Example exit gas analysis and RQ control (fed-batch) for an S. cerevisiae bioprocess
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INFORS HT Gas Analyser has been developed in particular for the exit gas analysis of bioprocesses.
The collected data on O2 and CO2 can be used for metabolic studies and bioprocess control.
- Immediate readings for culture analysis
Direct deductions as to the condition of the culture can be made during the actual bioprocess from the O2 and CO2 readings.
- Precision control of bioprocesses
The Iris software allows the calculation of parameters such as the CO2 evolution rate (CER), the O2 uptake rate (OUR) and the resulting respiratory quotient (RQ). This in turn makes it possible to adopt a systematic approach to bioprocess control, to maintain specific metabolic states and to prevent O2 limitations or substrate limitations.
- Compatible with other bioreactors
The gas analyser can be operated with both bench-top bioreactors and in situ sterilisable bioreactors. The analogue connection also enables analysis of exit gases from bioreactors supplied by other manufacturers.
- Compact
With a footprint of just 115 x 235 mm, the gas analyser can be mounted on a workbench or in a rack.
- Optional multiplexer function for parallel bioreactors
The multiplexer function allows the INFORS HT gas analyser to read the O2 and CO2 levels on up to six INFORS HT parallel bioreactors (Multifors or Labfors).
- Online data acquisition
Data can be logged, archived, formatted into graphs and used for calculations and control algorithms using the Iris software – from any workstation.
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